RPSA/Laminin Receptor antibody

Catalog No. ABIN6654392

This anti-RPSA/Laminin Receptor antibody is a Mouse Monoclonal antibody detecting RPSA/Laminin Receptor in WB and IHC (p). Suitable for Human.

Quick Overview for RPSA/Laminin Receptor antibody (ABIN6654392)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPSA/Laminin Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LMNR-1

Product Details anti-RPSA/Laminin Receptor Antibody

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: Recombinant full length protein was used as the immunogen for the RPSA antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the RPSA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Western blot: 1-2 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the RPSA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Alternative Name: RPSA / 40S Ribosomal protein SA

Background: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. [UniProt]

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly